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. Author manuscript; available in PMC: 2017 May 10.
Published in final edited form as: Stat Med. 2015 Dec 6;35(10):1595–1615. doi: 10.1002/sim.6819

Table 6.

Bias and Relative MSE (in relation to model (a) that respects the design features of a SMART) of estimates from the slope model and the quadratic model. Δ1AUC = the constrast in AUC between DTRs (1, 1) and (1, −1); Δ2AUC = the contrast in AUC between DTRs (−1, ·) and (1, −1). Bias that significantly differs from zero is in bold.

Effect Size N = 100
Δ1AUC

Δ2AUC

Bias × 100
Slope
Quad RMSE
Slope
Quad Bias × 100
Slope
Quad RMSE
Slope
Quad




0 0.1 1.7 1.67 1.87 −5.2 −1.9 0.71 1.55
0.2 35.4 13.5 1.89 1.73 19.7 −0.7 0.77 1.48
0.5 98.6 33.6 2.7 1.6 50.1 14.9 0.98 1.49
0.8 161.8 65.6 2.91 1.35 79 33.9 1.32 1.37
Effect Size N = 300
Bias × 100
Slope
Quad RMSE
Slope
Quad Bias × 100
Slope
Quad RMSE
Slope
Quad




0 0.1 0 1.71 1.71 3.4 5.4 0.72 1.43
0.2 41 10.7 2.57 1.69 20.9 6.2 0.85 1.45
0.5 105.5 25.7 5.17 1.57 54.5 10.7 1.53 1.44
0.8 189.2 36 7.87 1.34 96 17 2.97 1.38