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. Author manuscript; available in PMC: 2016 May 22.
Published in final edited form as: Hum Mutat. 2014 Apr 7;35(5):585–593. doi: 10.1002/humu.22534

Figure 2.

Figure 2

A: Crystal structure (PDB id: 3I2B) depicting a R25Q variation in the PTSPTS interacting domain but not at an interface residue and a R9C variation outside the interaction interface. B: Y2H assay illustrating that the R25Q variation disrupts the PTSPTS interaction, whereas the R9C variation does not affect the interaction.