Table 4.
PCO2 and pH data from the present study and the three other major studies
| PAPER | Present study | Swenson et al. 1991 | Kronenberg and Cain 1968a | Swenson and Hughes 1993 | ||
|---|---|---|---|---|---|---|
| Drug | Benz | Benz | Benz | Acet | ||
| Duration | Days | 24 h | 24 h | 72 h | Acute i.v. | 24 h |
| Condition | Altitude | Sea level | Chamber | Chamber | Sea level | Sea level |
| pHa | ||||||
| Placebo | 7.442 | 7.44 | 7.493 | 7.501 | 7.43 | 7.44 |
| Inhibitor | 7.408 | 7.39 | 7.437 | 7.445 | 7.44 | 7.40 |
| PaCO2 | ||||||
| Placebo | 27.0 | 39.4 | 28.5 | 27.3 | 41.2 | 39.9 |
| Inhibitor | 23.6 | 36.0 | 26.7 | 25.8 | 38.0 | 35.3 |
| PaCO2 fall | 3.4 | 3.4 | 1.8 | 1.5 | 3.2 | 4.6 |