Table 3.
Risk of bias in included study
| Lee et al. 2009 10 | ||
|---|---|---|
| Bias | Authors' judgement | Support for judgement |
| Random sequence generation (selection bias) | Unclear risk | Method of randomization not mentioned in detail. Randomization was stratified by encephalopathy grade with a blocking factor of 4. |
| Allocation concealment (selection bias) | High risk | Not mentioned |
| Blinding of participants and personnel (performance bias) | Low risk | Double‐blind. Participants and all study personnel, except biostatisticians and site pharmacist were blinded. |
| Blinding of outcome assessment (detection bias) | Low risk | Double‐blind. All study personnel except biostatisticians and site pharmacist were blinded. |
| Incomplete outcome data (attrition bias) | Low risk | Intention‐to‐treat analysis. All participants analyzed in the group they were randomized to. No missing data. |
| Selective reporting (reporting bias) | Low risk | No |
| Other bias | Low risk | No |