Table 2.
Efficacy of treating pain on psychosis and agitation.
| Baseline | 8 weeks | ||||||
|---|---|---|---|---|---|---|---|
| Control (n = 177) | Intervention (n = 175) | p a | Control (n = 157) | Intervention (n = 146) | p a | p changeb | |
| NPI total score | 31.4 (21.4) | 34.8 (21.9) | 0.132 | 26.6 (20.1) | 18.9 (17.5) | <0.001 | <0.001 |
| Psychosis cluster | 4.8 (5.8) | 6.1 (6.9) | 0.087 | 3.7 (4.9) | 3.9 (5.5) | 0.682 | 0.091 |
| Delusion | 2.6 (3.8) | 3.6 (4.3) | 0.030 | 2.0 (3.1) | 2.0 (3.2) | 0.813 | 0.052 |
| Hallucination | 1.5 (2.9) | 1.8 (3.2) | 0.427 | 1.1 (2.3) | 1.4 (2.7) | 0.405 | 0.832 |
| Euphoria | 0.7 (2.0) | 0.8 (2.2) | 0.887 | 0.6 (1.9) | 0.5 (1.8) | 0.123 | 0.507 |
| Agitation cluster | 13.4 (10.9) | 14.8 (10.9) | 0.155 | 11.3 (10.9) | 7.8 (8.3) | 0.007 | <0.001 |
| Agitation/aggression | 3.7 (3.9) | 4.2 (4.3) | 0.373 | 3.4 (3.8) | 2.1 (3.1) | 0.001 | 0.001 |
| Disinhibition | 3.0 (4.0) | 2.9 (3.8) | 0.922 | 2.6 (3.9) | 1.7 (3.0) | 0.061 | 0.293 |
| Irritability | 3.7 (3.7) | 4.2 (4.1) | 0.338 | 3.0 (3.4) | 2.3 (3.1) | 0.092 | 0.093 |
| Abb. motor behaviour | 3.0 (4.5) | 3.5 (4.7) | 0.328 | 2.4 (3.7) | 1.7 (3.6) | 0.052 | 0.017 |
aCalculated by analyzing the difference between the intervention group and control group at each measurement point using the Mann-Whitney U test.
bCalculated by analyzing the difference in change of NPI-NH score in the intervention group versus the control group from baseline to Week 8 using the Mann-Whitney U test.