Table 3.
Event Details
| Age (years) | % YST at Diagnosis* | AFP Level (IU/L) |
Relapse Confirmed by | Time to Relapse (months)† | Survival |
||
|---|---|---|---|---|---|---|---|
| Diagnosis | Relapse | Status | Survival Time (months) | ||||
| Concordant-stage patients‡ | |||||||
| 2 | 2 | 9,610 | 153 | AFP only | 4 | Alive | 42.1 |
| 9 | 99 | 3,772 | 3,773 | AFP only | 7 | Alive | 79.6 |
| 13 | 100 | 497 | 39 | Pelvic mass | 5 | Alive | 35.8 |
| 13 | 60 | 17,285 | 915 | Retroperitoneal mass | 4 | Alive | 43.3 |
| 13 | 100 | 26,773 | 305 | Pelvis and retroperitoneum | 2 | Alive | 28.2 |
| 13 | 100 | 889 | 446 | AFP only | 4 | Alive | 23.4 |
| 15 | 99 | 44,115 | 792 | Pelvis, liver, pleura | 2 | Alive | 57.7 |
| 16 | 100 | 56,221 | 476 | Para-aortic mass | 1 | Alive | 29.1 |
| 16 | 50 | 494 | 998 | Unknown site of mass | 1 | Dead | 16.2 |
| Discordant-stage patients‡ | |||||||
| < 1 | Unknown | 156 | 327 | Retroperitoneal mass | 2 | Alive | 22.1 |
| 10 | 25 | 13,310 | 146 | Liver | 3 | Alive | 42.4 |
| 11 | 100 | 2,220,000 | 342 | AFP only | 2 | Alive | 27.9 |
Abbreviations: AFP, alpha-fetoprotein; YST, yolk sac tumor.
Percentage of the tumor that was YST at diagnosis.
Time to relapse defined as time from initial definitive surgery to first relapse.
Concordant or discordant means that central review of stage by study surgeons was either concordant or discordant with stage determined by institution.