Table 3. Free-response receiver operating characteristic (FROC) and receiver operating characteristic (ROC) analysis in the sentinel lymph node experiment.
| FROC analysis | 1 FP | 2 FP |
|---|---|---|
| Sensitivity (incl. ITC) | 0.71 (0.39–0.93) | 0.74 (0.59–0.94) |
| Sensitivity (excl. ITC) | 0.90 (0.63–0.99) | 0.93 (0.78–1.0) |
| ROC analysis | Area under the curve | Specificity at 99.9% sensitivity |
| Test (incl. ITC) | 0.88 (0.77–0.97) | 0.39 (0.33–0.90) |
| Test (excl. ITC) | 0.90 (0.79–0.98) | 0.39 (0.32–0.94) |
| consecutive (incl. ITC) | 0.74 (0.65–0.82) | 0.02 (0.01–0.30) |
| consecutive (excl. ITC) | 0.88 (0.81–0.93) | 0.44 (0.43–0.69) |
Mean bootstrap values are given for sensitivity (FROC analysis), area under the curve (ROC analysis) and specificity at 99.9% sensitivity (ROC analysis). 95th-percentile confidence intervals obtained through bootstrapping are shown between brackets. (FP = False positive detections per tumor-negative image).