Table A4.
OS by Prognostic Factors and Cytogenetic Subgroups
| Characteristic | No. of Patients | OS (days) | Patient Status After 30-Month Follow-Up |
|||||
|---|---|---|---|---|---|---|---|---|
| Alive |
Dead |
Lost to Follow-Up |
||||||
| No. | % | No. | % | No. | % | |||
| Binet stage | ||||||||
| B | 44 | NR | 40 | 90.0 | 4 | 9.1 | 0 | 0.0 |
| C | 56 | NR | 44 | 78.6 | 11 | 19.6 | 1 | 1.8 |
| Age, years | ||||||||
| < 65 | 28 | NR | 25 | 89.3 | 3 | 10.7 | 0 | 0.0 |
| ≥ 65 | 72 | NR | 59 | 81.9 | 12 | 16.7 | 1 | 1.4 |
| Responders | ||||||||
| CR/PR | 84 | NR | 76 | 90.5 | 7 | 8.3 | 1 | 1.2 |
| Nonresponders | 15 | NR | 8 | 53.3 | 7 | 46.7 | 0 | 0.0 |
| IgVH status | ||||||||
| Mutated | 36 | NR | 28 | 77.8 | 7 | 19.4 | 1 | 2.8 |
| Normal | 52 | NR | 48 | 92.3 | 4 | 7.7 | 0 | 0.0 |
| 17p deletion status | ||||||||
| Deleted | 0 | NE | NE | NE | NE | |||
| Normal | 86 | NR | 74 | 86.0 | 11 | 12.8 | 1 | 1.2 |
| 11q deletion status | ||||||||
| Deleted | 13 | NR | 10 | 76.9 | 3 | 23.1 | 0 | 0.0 |
| Normal | 76 | NR | 67 | 88.2 | 8 | 10.5 | 1 | 1.3 |
| 12q trisomy status | ||||||||
| +12q | 16 | NR | 15 | 93.8 | 1 | 6.3 | 0 | 0.0 |
| Normal | 73 | NR | 62 | 84.9 | 10 | 13.7 | 1 | 1.4 |
| 13q deletion status | ||||||||
| Deleted | 43 | NR | 38 | 88.4 | 5 | 11.6 | 0 | 0.0 |
| Normal | 46 | NR | 39 | 84.8 | 6 | 13.0 | 1 | 2.2 |
Abbreviations: CR, complete response; NE, not evaluated; NR, not reached; OS, overall survival; PR, partial response.