Table 1.
Differentially abundant genera between Cluster 1 (contains Mq quarters) and Cluster 2 (contains Hq quarters) as determined by the LEfSe pipeline.
| Taxonomic unit | Average abundance | Median abundance | Standard deviation | LDA score | pval | ||||
|---|---|---|---|---|---|---|---|---|---|
| Phylum | Genera | C1 | C2 | C1 | C2 | C1 | C2 | ||
| GENERA MORE ABUNDANT IN CLUSTER 1 | |||||||||
| Firmicutes | Staphylococcus | 33.97 | 6.70 | 28.62 | 2.62 | 25.16 | 8.52 | 5.12 | 0.0015 |
| GENERA MORE ABUNDANT IN CLUSTER 2 | |||||||||
| Euryarchaeota | Methanocorpusculum | 0.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.05 | 3.07 | 0.0134 |
| Actinobacteria | Bifidobacterium | 1.91 | 4.23 | 1.54 | 3.99 | 1.85 | 1.48 | 4.01 | 0.0010 |
| [Prevotella] | 0.23 | 0.72 | 0.07 | 0.62 | 0.40 | 0.59 | 3.40 | 0.0010 | |
| CF231 | 0.37 | 1.79 | 0.32 | 1.77 | 0.32 | 1.36 | 3.87 | 0.0010 | |
| YRC22 | 0.11 | 0.34 | 0.10 | 0.38 | 0.12 | 0.18 | 3.11 | 0.0076 | |
| 5-7N15 | 1.32 | 4.46 | 1.21 | 4.72 | 1.12 | 1.61 | 4.20 | 0.0001 | |
| Bacteroides | 0.22 | 0.92 | 0.12 | 0.86 | 0.24 | 0.49 | 3.57 | 0.0002 | |
| Paludibacter | 0.18 | 0.57 | 0.11 | 0.61 | 0.17 | 0.45 | 3.35 | 0.0116 | |
| Parabacteroides | 0.02 | 0.09 | 0.00 | 0.08 | 0.04 | 0.07 | 2.86 | 0.0015 | |
| Prevotella | 0.26 | 1.00 | 0.16 | 0.89 | 0.32 | 0.35 | 3.57 | 0.0001 | |
| Hymenobacter | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.01 | 2.78 | 0.0473 | |
| Firmicutes | Leuconostoc | 0.01 | 0.04 | 0.00 | 0.03 | 0.03 | 0.04 | 2.76 | 0.0265 |
| Turicibacter | 0.30 | 0.65 | 0.23 | 0.45 | 0.29 | 0.52 | 3.22 | 0.0346 | |
| Clostridium | 0.16 | 0.50 | 0.12 | 0.36 | 0.11 | 0.37 | 3.23 | 0.0004 | |
| [Ruminococcus] | 0.13 | 0.24 | 0.09 | 0.20 | 0.12 | 0.12 | 2.78 | 0.0059 | |
| Blautia | 0.08 | 0.20 | 0.05 | 0.17 | 0.08 | 0.12 | 2.88 | 0.0043 | |
| Butyrivibrio | 0.95 | 1.54 | 0.74 | 1.36 | 0.70 | 0.82 | 3.46 | 0.0435 | |
| Coprococcus | 0.07 | 0.25 | 0.05 | 0.20 | 0.08 | 0.15 | 2.99 | 0.0003 | |
| Dorea | 0.54 | 1.10 | 0.48 | 0.99 | 0.39 | 0.45 | 3.39 | 0.0033 | |
| Lachnospira | 0.01 | 0.03 | 0.00 | 0.01 | 0.01 | 0.03 | 3.16 | 0.0360 | |
| Roseburia | 0.28 | 0.89 | 0.20 | 0.81 | 0.34 | 0.41 | 3.50 | 0.0002 | |
| rc4-4 | 0.08 | 0.27 | 0.03 | 0.21 | 0.15 | 0.22 | 3.00 | 0.0020 | |
| Oscillospira | 0.48 | 1.61 | 0.44 | 1.50 | 0.40 | 0.64 | 3.75 | 0.0001 | |
| Ruminococcus | 2.80 | 9.21 | 2.67 | 9.12 | 1.69 | 2.61 | 4.49 | 0.0000 | |
| Anaerovibrio | 0.05 | 0.42 | 0.02 | 0.34 | 0.06 | 0.46 | 3.28 | 0.0002 | |
| Dialister | 0.00 | 0.02 | 0.00 | 0.00 | 0.00 | 0.04 | 2.51 | 0.0473 | |
| Phascolarctobacterium | 0.43 | 1.23 | 0.37 | 1.26 | 0.39 | 0.25 | 3.59 | 0.0002 | |
| Selenomonas | 0.01 | 0.06 | 0.00 | 0.04 | 0.02 | 0.05 | 3.13 | 0.0005 | |
| Succiniclasticum | 0.02 | 0.05 | 0.00 | 0.03 | 0.05 | 0.07 | 2.69 | 0.0092 | |
| Coprobacillus | 0.01 | 0.03 | 0.00 | 0.04 | 0.04 | 0.02 | 3.00 | 0.0057 | |
| Proteobacteria | Rhodoplanes | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.02 | 2.94 | 0.0473 |
| Sphingopyxis | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.01 | 3.06 | 0.0473 | |
| Desulfovibrio | 0.07 | 0.20 | 0.06 | 0.15 | 0.05 | 0.17 | 2.88 | 0.0088 | |
| Arcobacter | 0.00 | 0.03 | 0.00 | 0.00 | 0.01 | 0.05 | 2.58 | 0.0178 | |
| Marinospirillum | 0.05 | 0.20 | 0.00 | 0.19 | 0.10 | 0.14 | 2.95 | 0.0027 | |
| Spirochaetes | Treponema | 0.04 | 0.32 | 0.02 | 0.26 | 0.05 | 0.26 | 3.17 | 0.0009 |
| Tenericutes | RFN20 | 0.00 | 0.01 | 0.00 | 0.00 | 0.00 | 0.02 | 2.97 | 0.0473 |
| Verrucomicrobia | Akkermansia | 0.10 | 0.35 | 0.06 | 0.31 | 0.12 | 0.16 | 3.12 | 0.0003 |
Average and median abundances (expressed as percentages) as well as standard deviation are presented for each cluster. LEfSe results include LDA score and pval. The most discriminant genera (LDA score > 4) are in bold.