Table 1.
Participant characteristics in duloxetine and placebo groups on day 0 (baseline) and day 14 (post-drug).
| Duloxetine |
Placebo |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| (n = 19) | (n = 19) | ||||||||
| Sex | 9 male:10 female | 10 male:9 female | |||||||
| Age | 24.5 | (6.0) | 24.9 | (8.9) | |||||
| Body mass index | 22.8 | (2.3) | 21.1 | (1.6) | |||||
| Day 0 | Day 14 | Day 0 | Day 14 | p | |||||
| GAD-7 | 9.4 | (6.2) | 14.3 | (8.9) | 9.6 | (5.1) | 11.3 | (6.3) | 0.16 |
| PANAS positive | 34.9 | (5.7) | 33.6 | (6.7) | 35.3 | (4.1) | 33.6 | (4.4) | 0.83 |
| PANAS negative | 13.2 | (2.9) | 12.8 | (2.4) | 13.4 | (2.5) | 14.1 | (3.6) | 0.30 |
| Heart rate | 73.2 | (10.9) | 73.3 | (8.5) | 68.8 | (11.2) | 70.3 | (10.9) | 0.65 |
| Systolic BP | 124.8 | (8.4) | 124.3 | (9.4) | 125.1 | (8.6) | 119.2 | (10.5) | 0.06 |
| Diastolic BP | 71.6 | (9.6) | 71.2 | (8.0) | 69.5 | (9.2) | 66.2 | (7.0) | 0.27 |
Values represent mean (standard deviation). P value reflects drug × time interaction. GAD: Generalised Anxiety Disorder Screener; PANAS: positive and negative affect; BP: blood pressure.