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. 2016 Apr 27;6(7):930–947. doi: 10.7150/thno.14855

Figure 7.

Figure 7

(A) Chemical structures of the four polymers examined: a cationic dendronized poly-(3,5-bis(3-aminopropoxy)benzyl)-methacrylate (PG1), cationic ɑ-poly(D-lysine) (PDL), neutral methoxy PEG (mPEG) and anionic poly(acrylic acid) (PAA). (B) The uncleaved peptide substrate was incubated in vitro with MX, MX-polymer conjugates or endogenous enzymes. All MX-polymer conjugates induced a significant increase in fluorescence intensity after peptide cleavage. (C) The activity of the individual MX-polymer conjugates was measured using an in vivo fluorescence assay. Reproduced with permission from ref. 119. Copyright 2013, Nature Publishing Group.