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. 2016 Apr 28;6(7):1031–1042. doi: 10.7150/thno.14431

Figure 1.

Figure 1

Preparation and characterization of PDA-ICG-PEG.(a) A scheme showing the synthesis of PDA-ICG-PEG nanoparticles, as well as the followed drug loading and metal ion chelating. (b) A TEM image of PDA-ICG-PEG nanoparticles. (c) Dynamic light scattering (DLS) data of PDA and PDA-ICG-PEG nanoparticles in aqueous solutions. (d) UV-Vis-NIR spectra of PDA and PDA-ICG-PEG. Insert: a photo of PDA-ICG-PEG in different solutions: water (1), NaCl (2) and PBS (3). e) Temperature changes of water, PDA and PDA-ICG-PEG at same PDA concentrations (0.014 mg/ml) under irradiation by the 808-nm laser (0.8 W/cm2). (f) Temperature changes of PDA-ICG-PEG and free ICG solutions with the same ICG concentration under irradiation of the 808-nm laser with the power density of 0.8 W/cm2 for 5 cycles (3 min of irradiation for each cycle).Insert: Photos of free ICG and PDA-ICG-PEG solutions before (left) and after (right) laser irradiation.