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. 2015 Aug 17;64(12):4226–4237. doi: 10.2337/db15-0521

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© 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

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Differential expression of miRNA signatures in populations with diabetes and populations without diabetes with different propensities for endothelial differentiation. A: Heat map showing individual expression of miRNAs that are known to target clock genes in CD34 cells, eEPCs, and ECFCs. Highly altered miRNAs were further separated to identify unique miRNAs targeting Per2 (B) and Cry2 (C) mRNA. n = 3. D: qRT-PCR validating miRNA expression of miR-92a and let-7e. n = 8, control subjects without diabetes; n = 10, diabetes.