Table 1.
Cycle outcome in women receiving a reduced dose of r-hCG (125 µg) to trigger final oocyte maturation
| 125 μg r-hCG (n=35) | |
|---|---|
| Total dose of FSH administered (IU) | 1,648.00±77.04 |
| Duration of stimulation (days) | 11.18±1.70 |
| Number of dominant follicles with diameter >11 mm | 20.37±4.85 |
| Number of follicles with diameter >14 mm | 13.56±3.42 |
| Number of oocytes retrieved | 13.80±4.40 |
| Number of mature oocytes (MII) | 11.64±4.40 |
| Percentage of MII/oocytes retrieved | 84.9±16.1 |
| Fertilization rate | 88.0% |
| Implantation ratea | 14.74% (14/95) |
| Number of transferred embryos | 2.71±0.46 |
| Good quality embryos | 84.21% (80/95) |
| Biochemical pregnancy rate | 5.71% (2/35) |
| Early spontaneous abortion rate | 16.67% (2/12) |
| Clinical pregnancy rate | 34.26% (12/35) |
| Twin pregnancy rate | 2.86% (1/35) |
| Triplet pregnancy rate | 0.00% (0/35) |
| Delivery rate per clinical pregnancy | 83.33% (10/12) |
| Hormone serum levels | |
| On r-hCG day | |
| LH (mIU/mL) | 1.26±0.75 |
| Progesterone (ng/mL) | 1.27±0.61 |
| Estradiol (pg/mL) | 3,619.97±455.70 |
| hCG (mIU/mL) | 0.45±0.07 |
| On oocyte retrieval day | |
| LH (mIU/mL) | 0.35±0.30 |
| Progesterone (ng/mL) | 25.28±13.62 |
| Estradiol (pg/mL) | 2,349.80±335.05 |
| hCG (mIU/mL) | 72.08±9.21 |
| On embryo transfer day | |
| LH (mIU/mL) | 0.34±0.17 |
| Progesterone (ng/mL) | 182.63±91.80 |
| Estradiol (pg/mL) | 1,606.21±176.20 |
| hCG (mIU/mL) | 24.36±6.75 |
Notes: Data are expressed as mean ± standard deviation.
a
Implantation rate was defined as the number of fetal heartbeats at ultrasound at 7 weeks after transfer divided by the number of embryos transferred.
Abbreviations: r-hCG, recombinant human chorionic gonadotropin; FSH, follicle stimulating hormone; LH, luteinizing hormone; hCG, human chorionic gonadotropin.