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. Author manuscript; available in PMC: 2016 May 23.
Published in final edited form as: Science. 2015 Sep 18;349(6254):1338–1343. doi: 10.1126/science.aac5017

Fig. 4.

Fig. 4

Antigenic maps of the DENV panel made with antisera drawn from NHPs one and five months post-infection. (A) An antigenic map of 47 DENV isolates titrated against 36 NHP antisera drawn one month post-infection. Colored arrows (DENV1=yellow, DENV2=blue, DENV3=green, DENV4=red) show the change in antiserum positions between one and three months. The black arrows show the average shift in serum position for each DENV type. The star denotes the antigenic center for each DENV type. (B) An antigenic map of 37 DENV isolates titrated against 16 NHP antisera drawn five months post-infection. Arrows point from positions of antisera at three months to the corresponding five-month positions.