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. 2015 Mar 29;1(1):67–74. doi: 10.1016/j.dadm.2014.11.009

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© 2015 The Alzheimer’s Association. Published by Elsevier Inc.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Decreased plasma DES/CHO in patients with AD. (A) Comparison of plasma desmosterol-to-cholesterol ratio (DES/CHO) between 201 control and 200 AD subjects from a large Japanese cohort. (B) Comparison of plasma DES/CHO among male control (M_Cont), female control (F_Cont), male AD (M_AD), and female AD (F_AD) subjects. (C) Comparison of plasma DES/CHO between control subjects without APOE ε4 (nonE4_Cont) and with APOE ε4 (E4_Cont), and AD patients without APOE ε4 (nonE4_AD) and with APOE ε4 (E4_AD). (D) Comparison of plasma DES/CHO among groups classified as MMSE groups. ^∗P < .05; ^∗∗P < .01.