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. Author manuscript; available in PMC: 2016 May 23.
Published in final edited form as: Mol Imaging. 2012 Feb;11(1):47–57.

Figure 2.

Figure 2

The extraction of PARACEST effects of the amine and amide from experimental data by three lorentzian line shapes centered at 0, −11, and +8 ppm. The CEST spectrum (solid line, no symbol) of Yb-DO3A-oAA at pH 6.5 and 37°C was acquired with selective saturation applied at 12.2 μT for 6 s, from +20 ppm to −20 ppm in 1 ppm increments. The line-fitting output showed a lorentzian line shape of water that was symmetric about 0 ppm (solid line with triangles) and lorentzian line shapes of the CEST effects of the amine (solid line with open circles) and the amide (solid line with filled circles).