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. Author manuscript; available in PMC: 2016 Nov 5.
Published in final edited form as: Nature. 2016 May 5;533(7601):100–104. doi: 10.1038/nature17949

Figure 1. Immune signature of EVD at the time of admission.

Figure 1

a, Day of symptom onset at admission. b, Frequencies of CD8 T cells (left) and CD4 T cells (right) positive for the indicated markers. Black boxes represent fatal cases and blue boxes represent survivors. c, Plots of four survivors and four fatalities showing frequencies of CTLA-4+ CD8 T cells. d, Levels of plasma cytokines in fatal vs surviving EVD cases. Statistical analysis was performed by Mann-Whitney test: ns, not significant; * p≤0.05; ** p≤0.01; *** p≤0.001.