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. 2016 Apr 15;31(6):984–991. doi: 10.1093/ndt/gfw062

Table 4.

Nocturnal Trial: comparison of changes for frequent (six times per week) versus conventional (three times per week) in-center hemodialysis

Variable Trt Observed dataa (mean ± SD)
Adjusted means and treatment effectsb
(± SE or 95% CI)
Baseline Month 4 Month 12 Month 4
Month 12
Change from baseline Treatment comparison (6× versus 3×) Change from baseline Treatment comparison (6× versus 3×)
SPI II 32.0 ± 18.4 33.3 ± 19.1 33.0 ± 23.1 1.7 ± 2.4 −2.9
(−9.3–3.4)
+1.2 ± 2.8 −4.5
(−12.2–3.2)
33.8 ± 17.4 30.9 ± 16.3 29.8 ± 17.7 −1.3 ± 2.3 −3.3 ± 2.8
Hours of sleep 6.37 ± 1.45 6.72 ± 1.83 6.24 ± 1.55 0.25 ± 0.22 −0.13
(−0.75–0.49)
−0.16 ± 0.19 0.43
(−0.09–0.96)
6.51 ± 1.43 6.59 ± 1.70 6.80 ± 1.71 0.12 ± 0.23 +0.27 ± 0.19

SE, standard error; Trt, treatment frequency.

aStatistics apply to subjects with measures at all three time points.

bValues adjusted for baseline score.