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. 2016 Mar;2(1):3–16. doi: 10.18383/j.tom.2016.00121

Figure 1.

Figure 1.

The application of 89Zr-ferumoxytol for normal lymph nodes (LNs) and tumor-drained LNs (A). Top panel: the structure of 89Zr-ferumoxytol. Lower left panel: detection of normal axillary LNs by 89Zr-ferumoxytol in positron emission tomography (PET)/magnetic resonance imaging (MRI). Lower middle panel: detection of the tumor-drained LN in Hi-Myc mouse by 89Zr-ferumoxytol in PET/MRI. Down right upper panel: PET/MRI of prostate region showing that the drained LN is outside of the prostate organ (green circle). Down right lower panel: distant drained inguinal node is identified by 89Zr-ferumoxytol (red arrow). Reproduced with permission from Thorek et al (53). The application of 64Cu-labeled, MoS2/IONP hybrid nanomaterial for PET- and MRI-based tumor detection (B). The structure of 64Cu-labeled MoS2/IONP is shown along with PET and MRI results at 24-hour after injection. Significant tumor uptake was confirmed in PET (circle indicates the tumor location) with a “darkened” tumor area in the MRI. Reproduced with permission from Liu et al (62).