Table 1. General characteristics of the 295 study patients with and without renal dysfunction; mean ± SD, number (%).
| eGFR (mL/min per 1.73 m2) | UACR (mg/g) | |||||
|---|---|---|---|---|---|---|
| <60 (N = 56) | ≥60 (N = 239) | P | ≥30 (N = 130) | <30 (N = 165) | P | |
| Age (yr) | 76.8±9.1 | 65.4±14.0 | <0.001 | 70.1±12.8 | 65.6±14.5 | 0.006 |
| Female gender | 38 (67.9) | 100 (41.8) | <0.001 | 64 (49.2) | 74 (44.8) | 0.454 |
| Hypertension | 48 (85.7) | 173 (72.4) | 0.038 | 94 (72.3) | 127 (77.0) | 0.359 |
| Diabetes | 21 (37.5) | 62 (25.9) | 0.083 | 43 (33.1) | 40 (24.2) | 0.094 |
| Hyperlipidemia | 32 (57.1) | 119 (49.8) | 0.322 | 66 (50.8) | 85 (51.5) | 0.899 |
| Current smoking | 3 (5.4) | 72 (30.1) | <0.001 | 27 (20.8) | 48 (29.1) | 0.103 |
| Previous stroke | 9 (16.1) | 32 (13.4) | 0.601 | 18 (13.8) | 23 (13.9) | 0.982 |
| Ischemic heart disease | 15 (26.8) | 43 (18.0) | 0.136 | 20 (15.4) | 38 (23.0) | 0.101 |
| Atrial fibrillation | 24 (42.9) | 74 (31.0) | 0.089 | 54 (41.5) | 44 (26.7) | 0.007 |
| Valvular heart disease | 15 (26.8) | 41 (17.2) | 0.098 | 32 (24.6) | 24 (14.5) | 0.029 |
| Alcohol history | 1 (1.8) | 45 (18.8) | 0.002 | 18 (13.8) | 28 (17.0) | 0.463 |
| eGFR | 44.6±13.6 | 93.8±18.7 | <0.001 | 80.7±29.2 | 87.4±23.4 | 0.033 |
| UACR | 244.1±616.9 | 73.4±172.4 | <0.001 | 221.0±450.4 | 15.0±20.6 | <0.001 |
| Previous medication | ||||||
| antithrombotics | 42 (75.0) | 105 (43.9) | <0.001 | 67 (51.5) | 80 (48.5) | 0.603 |
| Statin | 25 (44.6) | 54 (22.6) | 0.001 | 29 (22.3) | 50 (30.3) | 0.124 |
| ARB or ACEI | 26 (46.4) | 86 (36.0) | 0.147 | 51 (39.2) | 61 (37.0) | 0.691 |
| NIHSS at admission | 6.5±7.4 | 5.0±7.1 | 0.161 | 8.1±9.3 | 3.1±3.7 | <0.001 |
SD, standard deviation; eGFR, estimated glomerular filtration rate; UACR, urinary albumin-to-creatinine ratio; ARB, angiotensin receptor blocker; ACEI, angiotensin converting enzyme inhibitor; NIHSS, National Institutes of Health Stroke Scale.