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. Author manuscript; available in PMC: 2016 May 23.
Published in final edited form as: J Med Chem. 2013 Nov 11;56(22):9045–9056. doi: 10.1021/jm400904m

Figure 4.

Figure 4

µ-opiod receptor affinity of 20e compared to naloxone and morphine in Human Recombinant µ-Opioid Receptor OPRM1 Stable Cell Line.a.

aMorphine IC50 2.5±0.05 nM (Inline graphic), Naloxone IC50 1.87±0.07 nM (Inline graphic), 20e IC50 580±0.11 nM (Inline graphic)