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. 2016 May 23;11(5):e0156123. doi: 10.1371/journal.pone.0156123

Table 2. Cerebellum and brainstem volume (ml) calculated after FreeSurfer automated process, manual correction and corrective learning in the test set using training set of 2 and 5 scans.

FreeSurfer Manual Correction Training Set of 2 Scans Training Set of 5 Scans
Cerebellum
 Younger controls, 8 channel 140 ± 13* 132 ± 12 133 ± 12 133 ± 12
 Younger controls, 32 channel 150 ± 17* 144 ± 16 145 ± 17 145 ± 17
 Older controls, 32 channel 130 ± 12* 124 ± 10 125 ± 10 125 ± 10
 Older patients, 32 channel 115 ± 16* 110 ± 15 112 ± 15 111 ± 15
Brainstem
 Younger controls, 8 channel 22.8 ± 2.0* 31.1 ± 2.6 30.1 ± 2.3* 30.2 ± 2.3*
 Younger controls, 32 channel 26.1 ± 4.0* 34.5 ± 5.3 33.2 ± 4.4* 33.2 ± 4.4*
 Older controls, 32 channel 23.5 ± 1.9* 31.7 ± 2.4 30.6 ± 2.2* 30.8 ± 2.3*
 Older patients, 32 channel 20.7 ± 2.6* 27.2 ± 3.6 26.4 ± 3.2* 26.4 ± 3.2*

*, significant at FDR 5% compared with manual correction, p ≤ 0.010.