Table 4. Comparison between the Korean Risk Score and risk prediction models of laboratory parameters.
Korean Risk Score (KRS) | FPG model | HbA1c model | FPG and HbA1c model | Combined risk prediction model of KRS, FPG, and HbA1c (CRPM) | |
---|---|---|---|---|---|
AROC(95% CI) | 0.696 (0.655–0.737) | 0.771 (0.729–0.813) | 0.796 (0.758–0.834) | 0.838 (0.804–0.871) | 0.849 (0.818–0.880) |
Change in AROC* (P value) | 0.075 (0.011) | 0.100 (<0.001) | 0.142 (<0.001) | 0.153 (<0.001) | |
NRI (%)* (P value) | 27.3 (<0.001) | 27.8 (<0.001) | 45.2 (<0.001) | 52.1 (<0.001) | |
IDI* (P value) | 0.046 (<0.001) | 0.058 (<0.001) | 0.099 (<0.001) | 0.105 (<0.001) | |
Change in AROC† (P value) | 0.011 (0.016) | ||||
NRI (%)† (P value) | 4.6 (0.264) | ||||
IDI† (P value) | 0.006 (0.176) |
Abbreviations: AROC, area under the curve of receiver operating characteristic curve; FPG, fasting plasma glucose; HbA1c, hemoglobin A1c; NRI, net reclassification index; IDI, integrative discrimination improvement.
*Changes in AROC, NRI, and IDI were calculated for each model compared to the KRS.
†Changes in AROC, NRI and IDI were calculated to compare FPG and HbA1c models and combined risk prediction models of KRS, FPG, and HbA1c.