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. Author manuscript; available in PMC: 2016 May 23.
Published in final edited form as: Small. 2010 Jul 19;6(14):1520–1528. doi: 10.1002/smll.200902409

Figure 5.

Figure 5

Whole-body imaging and renal clearance of silica-coated QDs. (A) Representative whole-body fluorescence images of a nude mouse injected with silica-coated QDs during 30 min time course. A strong signal from bladder was observed, indicating the possible renal clearance of silica-coated QDs. (Five mice were examined for the study and the results remain consistent.) (B) Representative whole-body fluorescence images of a nude mouse injected with Invitrogen QD605 during 30 min time course. The main signal comes from the liver. (Five mice were examined for the study and the results remain consistent.) (C) Size exclusion chromatography analysis of urine samples collected from nude mice injected with silica-coated QDs (red line) and 1X PBS (black line). The peak at 30 nm correlates with QDs signal. The amount of urinarily excreted silica-coated QDs is about 2% of the totally injected dose.