Table 2.
DAVID biological process enrichment analysis of chicken proteins isolated by SNV 5’ UTR (+1–602)
| Identifier term Activity (Protein count) |
Fold enrichment p-value |
Proteins |
|---|---|---|
| Transcription and mRNA Processing | ||
| GO:0010467 gene expression (n= 32) |
37 9.107E-22 |
RPL19, RPL14, RPL13, SNRPD3, RPL15, SNRPD1, SYNCRIP, RPS2, YBX1, NONO, RPS3A, RPLP0, TARDBP, RPLP1, U2AF1, RPL11, RPL12, PTBP1, HNRNPA2B1, RPS4X, HNRNPR, HNRNPU, HNRPDL, RPS16, RPS14, SNRNP200, THOC4, RPS10, RPL35, RPS15A, HNRNPA3, RPS25, HNRNPM, RPS26, RPL6, RPL31, RPL9, RPL3, PABPC1, RPL7A, RPS23, RPSA, EEF1A1, RPL27, RPL23A, DDX5, RPS7, HNRNPH3, ILF2, RPL22, SFPQ, HNRNPH1 |
| GO:0006396 RNA processing (n= 26) |
10 1.019E-18 |
RPL14, SNRPD3, SNRPD1, SYNCRIP, YBX1, NONO, HNRNPA3, HNRNPM, TARDBP, U2AF1, RPL11, PABPC1, PTBP1, HNRNPA2B1, DDX5, HNRNPR, HNRNPU, RPS7, HNRPDL, HNRNPH3, RPS16, RPS14, SFPQ, SNRNP200, THOC4, HNRNPH1 |
| GO:0008380 RNA splicing (n=20) |
15 3.112E-17 |
SNRPD3, PTBP1, HNRNPA2B1, SNRPD1, SYNCRIP, DDX5, HNRNPR, HNRNPU, YBX1, NONO, HNRNPA3, HNRNPM, HNRNPH3, TARDBP, SFPQ, SNRNP200, U2AF1, THOC4, PABPC1, HNRNPH1 |
| GO:0043489 RNA stabilization n= 6 |
83 5.990E-09 |
ELAVL1, SYNCRIP, IGF2BP1, PABPC1, HNRNPU, YBX1 |
| GO:0022613 ribonucleoprotein complex biogenesis n= 10 |
12 1.652E-07 |
RPL14, RPS16, RPS14, RPLP0, SNRPD3, SNRNP200, SNRPD1, RPL11, RPL7A, RPS7 |
| Translation/Ribosome Biogenesis | ||
| GO:0006412 translation n= 30 |
19 5.445E-30 |
RPL19, RPL14, RPL13, RPL15, RPL35, RPS15A, RPS2, RPS25, RPS26, RPL31, RPS3A, RPL6, RPLP0, RPL9, RPLP1, RPL3, RPL11, RPL12, RPL7A, RPS23, RPSA, EEF1A1, RPL27, RPL23A, RPS4X, RPS7, RPS16, RPL22, RPS14, RPS10 |
| GO:0042254 ribosome biogenesis n= 7 |
12 2.390E-05 |
RPL14, RPS16, RPS14, RPLP0, RPL11, RPL7A, RPS7 |
| Other | ||
| GO:0010608 posttranscriptional regulation of gene expression n= 8 |
8 6.138E-05 |
UPF1, ELAVL1, SYNCRIP, IGF2BP1, PABPC1, RPS4X, HNRNPU, YBX1 |
| GO:0006364 rRNA processing n= 5 |
5 9.465E-04 |
RPL14, RPS16, RPS14, RPL11, RPS7 |
*
Started with Terms with p value greater than 0.05, removed redundant and less meaningful BP Categories, rounded fold enrichment and p values. Overrepresented GO categories were clustered by their relationship to the steps of gene expression (transcription, splicing, and translation).