Table 3.
DAVID biological process enrichment analysis of chicken proteins isolated by RSV 5’ UTR (+1–380)
| Identifier term Activity (Protein count) |
Fold enrichment and (p-value) |
Proteins |
|---|---|---|
| Transcription and mRNA Processing | ||
| GO:0010467 gene expression (34) |
3 (3.194E-09) |
RPL15, RPL35, SYNCRIP, POLR2B, KARS, SF3B3, RPS3, SF3B1, FUBP3, DDX17, RPL6, RPS3A, RPL31, PRPF8, RPL8, RPLP1, HNRNPD, RPL11, SSRP1, EEF1A1, EIF2S3, SSB, ILF3, RPS6, DDX5, HNRNPR, SARS2, HNRNPU, ILF2, RPS14, WDR3, RPS10, HNRNPH1, LRPPRC |
| GO:0006396 RNA processing (16) |
7 3.512E-09 |
SYNCRIP/HNRNPQ, SSB, RPS6, DDX5, HNRNPR, SF3B3, POLR2B, HNRNPU, SF3B1, DDX17, RPS14, PRPF8, HNRNPD, WDR3, RPL11, HNRNPH1 |
| GO:0008380 RNA splicing (10) |
8 (2.137E-06) |
SF3B1, PRPF8, HNRNPD, SYNCRIP, HNRNPH1, DDX5, HNRNPR, HNRNPU, SF3B3, POLR2B |
| GO:0048255 mRNA stabilization (3) |
47.9 (1.683E-03) |
HNRNPD, SYNCRIP, HNRNPU |
| Translation/Ribosome Biogenesis | ||
| GO:0006412 translation (16) |
12 3.107E-12 |
EEF1A1, RPL15, RPL35, EIF2S3, RPS6, KARS, SARS2, RPS3, RPS3A, RPL6, RPL31, RPS14, RPLP1, RPL8, RPS10, RPL11 |
| GO:0006364 rRNA processing (4) |
10 6.382E-03 |
RPS14, WDR3, RPL11, RPS6 |
| GO:0016072 rRNA metabolic process (4) |
10.0 7.178E-03 |
RPS14, WDR3, RPL11, RPS6 |
| GO:0042254 ribosome biogenesis (4) |
8 1.376E-02 |
RPS14, WDR3, RPL11, RPS6 |
| GO:0006413 translational initiation (3) |
16 1.467E-02 |
RPS3A, EIF2S3, RPS3 |
| GO:0042274 ribosomal small subunit biogenesis (2) |
43.5 4.430E-02 |
RPS14, RPS6 |
| Other | ||
| GO:0034660 ncRNA metabolic process (7) |
7 3.497E-04 |
RPS14, WDR3, RPL11, SSB, RPS6, SARS2, KARS |
| GO:0030705 cytoskeleton-dependent intracellular transport (4) |
18 1.261E-03 |
KIF3B, MYH9, TPM1, LRPPRC |
| GO:0034470 ncRNA processing (5) |
6 7.250E-03 |
RPS14, WDR3, RPL11, SSB, RPS6 |
| GO:0007018 microtubule-based movement (4) |
8.5 1.120E-02 |
KIF3B, TUBB2C, TUBA3E, LRPPRC |
| GO:0006334 nucleosome assembly (3) |
8.5 4.667E-02 |
H1F0, H2AFZ, H3F3C |
*
Started with Terms with p value greater than 0.05, removed redundant and less meaningful BP Categories, rounded fold enrichment and p values. Overrepresented GO categories were clustered by their relationship to the steps of gene expression (transcription, splicing, and translation).