Table 2.

Functionally enriched clusters with ≥5 genes and significant enrichment scores >1.3 from DAVID analysis, from tests of the response to FW vs. SW for An. merus age 18 h and 66 h. There were no clusters with ≥5 genes and scores >1.3 for An. merus at 20% vs. 0%. Neither species had enriched clusters at 10% vs. 0%, and the only significantly enriched cluster for An. coluzzii at 20% vs. 0% was peptidase/immune, with 7 genes and a score of 2.31.

DAVID Cluster	Functional Category	Enrichment Score	Genes in Cluster
18 h, 30% vs. 0%
Cluster 1	serine peptidase, caspase, protease	2.75	10
Cluster 2	peptidase C14, caspase	2.75	7
18 h, 40% vs. 0%
Cluster 1	peptidase, caspase	3.58	20
Cluster 4	cuticle	2.00	6
18 h, 50% vs. 0%
Cluster 1	peptidase, CLIP domain serine protease, caspase	6.01	47
Cluster 2	cuticle	5.06	15
Cluster 3	fibrinogen	3.76	7
Cluster 4	cell cycle, mitosis, meiosis, kinase	2.61	15
Cluster 5	microtubule	2.17	17
Cluster 6	gustatory receptor, odorant receptor	1.60	13
Cluster 7	peptidyl-dipeptidase	1.48	8
Cluster 8	EGF	1.38	8
Cluster 9	transporter, sugar transporter	1.34	11
66 h, 50% vs. 0%
Cluster 1	peptidase, CLIP domain serine protease, chymotrypsin	3.36	32
Cluster 2	cellular retinaldehyde binding, alpha tocopherol	2.37	7
Cluster 3	fibrinogen	1.98	5
Cluster 4	odorant receptor, gustatory receptor	1.59	19
Cluster 5	C-type lectin	1.41	6
Cluster 6	transport, channel, receptor	1.33	32