Table 3.
Occurrence of venous thromboembolic disease during and after hospitalization and use of extended-duration low molecular weight heparin prophylaxis.
| In-hospital analysis | Post-discharge analysis | |||||||
|---|---|---|---|---|---|---|---|---|
| VTE in-hospital | VTE post-hospital* | LMWH post hospital*ǂ | ||||||
| N | N | (%) | N* | N | (%) | N | (%) | |
| Colectomy | ||||||||
| Colectomy (all) | 40,579 | 511 | (1.3) | 40,068 | 1,160 | (2.9) | 631 | (1.6) |
| Open | 29,647 | 432 | (1.5) | 29,215 | 922 | (3.2) | 489 | (1.7) |
| Laparoscopic | 10,932 | 79 | (0.8) | 10,853 | 238 | (2.2) | 142 | (1.3) |
| Oophorectomy | ||||||||
| Oophorectomy (all) | 10,456 | 196 | (1.9) | 10,260 | 376 | (3.7) | 1,259 | (12.3) |
| No cytoreduction | 6,836 | 132 | (1.9) | 6,704 | 267 | (4.0) | 998 | (14.9) |
| Cytoreduction | 3,620 | 64 | (1.8) | 3,556 | 109 | (3.1) | 261 | (7.3) |
| Hysterectomy | ||||||||
| Hysterectomy (all) | 14,640 | 122 | (0.8) | 14,518 | 307 | (2.1) | 1,305 | (9.0) |
| Abdominal hysterectomy | 8,623 | 107 | (1.2) | 8,516 | 227 | (2.7) | 886 | (10.4) |
| Laparoscopic hysterectomy | 3,779 | 9 | (0.2) | 3,770 | 54 | (1.4) | 262 | (7.0) |
| Robotic-assisted hysterectomy | 2,006 | 4 | (0.2) | 2,002 | 22 | (1.1) | 155 | (7.7) |
| Vaginal hysterectomy | 232 | 2 | (0.9) | 230 | 4 | (1.7) | 2 | (0.9) |
511, 196, 122 patients who had VTE during the hospitalization were excluded from the colectomy (N=40,068), oophorectomy (N=10,260), and hysterectomy (N=14,518) cohorts, respectively.
LMWH post-discharge hospital is defined as daily dose of enoxaparin ≤ 40 mg and/or dalteparin ≤ 5000 IU within 1 week after hospitalization (starting from date of discharge), and no VTE diagnosis before LMWH. 171, 147, and 166 patients who received therapeutic LMWH (enoxaparin > 40 mg and/or dalteparin > 5000 IU) and/or who had diagnosis of VTE before LMWH were grouped as no for LMWH post hospital in colectomy, oophorectomy and hysterectomy cohort respectively.