Table 3.
Enterotoxin | Strain | Variable positions in predicted amino acid SEC sequences | aa difference | ||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2 | 4 | 5 | 7 | 9 | 15 | 20 | 21 | 22 | 34 | 37 | 41 | 43 | 47 | 49 | 53 | 58 | 66 | 81 | 86 | 99 | 102 | 121 | 133 | 154 | 160 | 192 | 218 | 243 | 245 | 249 | total | sp | mp | ||
SEC3 |
S. aureus
Mu3 |
- | - | - | I | - | - | - | S | T | - | - | - | - | - | - | - | - | - | S | K | - | K | - | G | - | V | - | N | M | N | T | 12 | 3 | 9 |
SEC2 |
S. aureus
Tokyo12381 |
N | S | R | I | C | - | L | - | T | T | E | - | - | - | - | - | - | M | S | K | - | K | - | G | - | - | - | N | M | N | T | 18 | 7 | 11 |
SEC1 | S. aureus | N | S | R | I | C | - | L | - | T | T | - | A | K | - | E | V | - | - | S | K | G | K | - | G | - | - | - | N | M | N | T | 21 | 7 | 14 |
SECovine |
S. aureus
ED133 |
N | S | R | I | C | S | L | - | T | T | E | A | K | T | E | V | R | - | S | K | - | K | C | G | - | - | S | N | M | N | T | 26 | 8 | 18 |
SECbovine |
S. aureus
RF122 |
N | S | R | I | C | - | L | - | T | T | E | A | K | T | E | V | R | - | S | K | - | K | - | G | K | - | - | N | M | N | T | 24 | 7 | 17 |
SECepi |
S.
epidermidis 4S/FRI909 |
Y | R | L | V | R | A | I | F | I | M | D | S | E | L | G | Y | H | K | N | N | D | N | Y | S | N | I | N | S | I | K | M | - | - | - |
Signal peptide |
sp - signal peptide, mp - mature protein
Accession numbers (GenBank): SEC3 - S. aureus Mu3: AP009324.1 (complete genome), SEC2 - S. aureus Tokyo12381: AB860418.1 (SaPITokyo12381, complete sequence), SEC1: KF386012.1 (enterotoxin type C1 precursor gene), SECovine- S. aureus ED133: NC_017337.1 (complete genome), SECbovine- S. aureus RF122: NC_007622.1 (complete genome)