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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Neural Transm (Vienna). 2015 Nov 23;123(7):655–665. doi: 10.1007/s00702-015-1485-2

Figure 3. Correlation between the developmental decrease in REM sleep and N-type channel expression.

Figure 3

A) Developmental decrease in REM sleep as a percent of sleep time after Jouvet-Mounier et al (1970). In the rodent, the decrease occurs between 10 and 30 days before assuming adult levels. B) Relative quantity of N-type calcium channel (red lines) and P/Q-type calcium channel (blue lines) expression at 10 vs 30 days in punches from brain slices containing the PPN. Three replications in each of double samples showed that N-type channel expression significantly decreased >75%, while P/Q-type channel expression decreased <35%. C) Relative quantity of N-type calcium channel (red lines) and P/Q-type calcium channel (blue lines) expression at 10 vs 30 days in punches from brain slices containing the hippocampus (HIPP). N-type calcium channel (red lines) expression did not change between 10 and 30 days, while P/Q-type calcium channel (blue lines) expression increased ~50% during the same period in the HIPP. * p<0.05, ** p<0.01, NS not significant. Data from Garcia-Rill et al 2015.