Fig. 8.

Transient decrease in size of a squamous cell lung cancer in a 74-year-old man. (a) Unenhanced axial LDCT image of the chest shows a solid nodule in the upper right lobe with an irregular shape and a maximum diameter of 19 mm. (b) Follow-up LDCT scan obtained 1 month after antibiotic therapy demonstrated a significant regression of the lesion. (c) At LDCT obtained 3 months later, the nodule grew in size again. Biopsy was performed, and results of histology revealed lung adenocarcinoma. It is reported that adenocarcinomas can show a transient decrease in size, maybe related to fibrosis or atelectasis. In this cases, a further LDCT scan is suggested to assess the complete resolution or stability of the findings and to avoid missed diagnosis