Table 1.
Item | Value |
---|---|
Program invitation per person invited (one-off invitation letter and infrastructure cost) | £5 |
Cost of providing polypill (per person per day)c | £0.50, 0.75, 1.00, 1.25 and 1.50 |
Average healthcare cost of an MI (per clinical event)c | £29,900 [11, 15] |
Average healthcare cost of a stroke (per clinical event)c | £50,500 [12] |
Polypill uptake | 50 % |
Polypill adherence | 83 % [14] |
Polypill LDL cholesterol reductiona | 1.54 mmol/L [5] |
Polypill diastolic BP reductiona | 10.7 mmHg [6] |
Age-specific relative risk for MI on polypill at age 60b | 0.23 [5, 16] |
Age-specific relative risk for stroke on polypill at age 60b | 0.28 [5, 6, 16] |
aSimvastatin 20 mg, amlodipine 2.5 mg, hydrochlorothiazide 12.5 mg, losartan 25 mg
bAge-specific relative risks from age 50 were applied in the model
cAt 2014 prices