Table 5.
Sensitivity analyses relating to results shown in Table 3 for the “working case”
| Total saving from reducing incidence of MI and stroke (£bn) | Daily cost of Polypill Prevention Programme per person (£) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.50 | 0.75 | 1.00 | 1.25 | 1.50 | |||||||
| Total cost of Polypill Prevention Programme (£bn) | Net cost or saving (£bn) | Total cost of Polypill Prevention Programme (£bn) | Net cost or saving (£bn) | Total cost of Polypill Prevention Programme (£bn) | Net cost or saving (£bn) | Total cost of Polypill Prevention Programme (£bn) | Net cost or saving (£bn) | Total cost of Polypill Prevention Programme (£bn) | Net cost or saving (£bn) | ||
| (1) | (2) | (2–1) | (3) | (3–1) | (4) | (4–1) | (5) | (5–1) | (6) | (6–1) | |
| Incidence of MI and stroke | |||||||||||
| 25 % less | 2.22 | 2.41 | 0.18 | 3.61 | 1.39 | 4.81 | 2.59 | 6.01 | 3.79 | 7.21 | 4.99 |
| 25 % more | 2.98 | 2.36 | −0.63 | 3.53 | 0.55 | 4.71 | 1.73 | 5.88 | 2.90 | 7.06 | 4.08 |
| Polypill effectiveness | |||||||||||
| 25 % less | 2.09 | 2.09 | 0.26 | 3.53 | 1.44 | 4.71 | 2.61 | 5.88 | 3.79 | 7.06 | 4.96 |
| 25 % more | 3.14 | 2.40 | −0.74 | 3.60 | 0.46 | 4.80 | 1.66 | 6.00 | 2.86 | 7.20 | 4.06 |
| Cost of MI and stroke | |||||||||||
| 25 % less | 1.99 | 2.38 | 0.39 | 3.57 | 1.58 | 4.76 | 2.77 | 5.94 | 3.95 | 7.13 | 5.14 |
| 25 % more | 3.32 | 2.38 | −0.94 | 3.57 | 0.25 | 4.76 | 1.44 | 5.94 | 2.62 | 7.13 | 3.81 |
| Non-adherence to treatment | |||||||||||
| 25 % less | 2.79 | 2.50 | −0.29 | 3.75 | 0.96 | 5.00 | 2.21 | 6.25 | 3.46 | 7.50 | 4.71 |
| 25 % more | 2.52 | 2.26 | −0.26 | 3.39 | 0.87 | 4.51 | 2.00 | 5.64 | 3.12 | 6.77 | 4.25 |