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Colloid carcinoma of the breast. This invasive ducal carcinoma exhibits dominant mucin production and tumor cells are arranged in clusters and nests, floating in pools of extracellular mucin (a). Tumor cells are uniform in size and shape with hyperchromatic nuclei without prominent nucleoli and mitosis (b). PR (c) and ER (d) are positive in tumor cells. [(a) H&E, ×100; (b) H&E, ×400; (c) IHC, ×100; (d) IHC, ×100.]
