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. 2016 May 10;2016:6404082. doi: 10.1155/2016/6404082

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Copyright © 2016 P. J. Gagolewicz and H. C. Dringenberg.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of application (in V1 by means of reverse microdialysis) of either aCSF (n = 8; same group as in Figure 3) or WAY 100635 (1 mM, n = 10) on LTP following TBS (at arrow) of the LGN in urethane-anesthetized rats. Application of WAY 100635 resulted in a significant increase in LTP relative to control animals. Inserts depict typical fPSPs before (red) and after (blue) LTP induction in the presence of WAY 100635 (top) and aCSF (bottom; calibration bars indicate 0.5 mV vertical and 10 ms horizontal; each fPSP trace is an average of 30 min of continuous recording). ^∗ indicates a significant (P < 0.05, t-test) difference between the two groups.