Table 3.
Patient characteristics.
| Baseline | Placebo group (n = 20) | Liraglutide group (n = 14) | Placebo vs. liraglutide group | |
|---|---|---|---|---|
| mean (SEM) | mean (SEM) | P | ||
| Fasting plasma-glucose (mmol/L) | 5.8 (0.2) | 5.6 (0.2) | 0.24 | |
| Glycated hemoglobin (HbAlc) | 0.056 (0.001) | 0.055 (0.0006) | 0.41 | |
| Plasma-cholesterol total(mmol/L) | 5.9 (0.3) | 5.7 (0.2) | 0.67 | |
| Weight (kg) | 77.8 (3.0) | 74.1 (2.1) | 0.38 | |
| Body Mass Index (BMI) (kg/m | 25.1 (0.7) | 25.1 (1.0) | 0.96 | |
| Systolic blood pressure (mmHg) | 149.7 (4.3) | 144.1 (6.3) | 0.46 | |
| Diastolic blood pressure (mmHg) | 87.5 (2.4) | 83.9 (2.5) | 0.32 | |
| Heart rate (bpm) | 62.7 (3.2) | 64.8 (2.8) | 0.64 | |
| After 6 Months | Placebo group (n = 20) | Liraglutide group (n = 14) | Placebo vs. liraglutide group | Change placebo vs. change liraglutide group |
| mean (SEM) | mean (SEM) | P | P | |
| Fasting plasma-glucose (mmol/L) | 5.6 (0.1) | 5.1 (0.1) | 0.0041* | 0.10 |
| Glycated hemoglobin (HbAlc) | 0.056 (0.0008) | 0.054 (0.0008) | 0.23 | 0.68 |
| Plasma-cholesterol total (mmol/L) | 5.5 (0.3) | 5.1 (0.2) | 0.27 | 0.12 |
| Weight (kg) | 76.1 (2.8) | 69.2 (2.0) | 0.071 | 0.0083* |
| Body Mass Index (BMI) (kg/m | 24.6 (0.7) | 23.4 (0.9) | 0.26 | 0.0069* |
| Systolic blood pressure (mmHg) | 151.4 (4.8) | 132.4 (5.6) | 0.015* | 0.013* |
| Diastolic blood pressure (mmHg) | 88.8 (2.7) | 80.3 (2.5) | 0.035* | 0.19 |
| Heart rate (bpm) | 68.4 (4.3) | 66.1 (1.8) | 0.67 | 0.46 |
Data are presented as mean (SEM), and P-value is calculated using paired/independent samples t-test. ∗P < 0.05.