Table 2. Selected Variables by Multivariate Cox Proportional Hazards Regression Analysis and Prognostic Score.
| Variables | Hazard Ratio | 95% CI | P | Score |
|---|---|---|---|---|
| Age, year | <0.001 | |||
| <60 | Reference | 0 | ||
| 60–70 | 1.183 | 1.080–1.295 | <0.001 | 0.9 |
| >70 | 1.456 | 1.315–1.613 | <0.001 | 2.4 |
| Race | 0.007 | |||
| White | Reference | 0.4 | ||
| Black | 1.262 | 1.075–1.481 | 0.004 | 1.9 |
| Other | 0.916 | 0.764–1.098 | 0.344 | 0 |
| Histology | 0.002 | |||
| Adenocarcinoma | Reference | 0 | ||
| Squamous cell carcinoma | 1.174 | 1.060–1.299 | 0.002 | 1.0 |
| Tumor site | 0.002 | |||
| Upper | Reference | 2.6 | ||
| Middle | 1.013 | 0.795–1.291 | 0.914 | 2.7 |
| Lower | 0.842 | 0.664–1.067 | 0.154 | 1.4 |
| Overlapping | 0.910 | 0.666–1.245 | 0.556 | 1.9 |
| Unknown (X) | 0.638 | 0.457–0.890 | 0.008 | 0 |
| Tumor size (cm) | <0.001 | |||
| ≤3 | Reference | 0 | ||
| ≤5 | 1.247 | 1.116–1.393 | <0.001 | 1.3 |
| >5 | 1.359 | 1.209–1.527 | <0.001 | 1.9 |
| Unknown (X) | 1.151 | 1.027–1.289 | 0.016 | 0.8 |
| Grade | <0.001 | |||
| Well differentiated | Reference | 0 | ||
| Moderately differentiated | 1.311 | 1.062–1.617 | 0.012 | 1.4 |
| Poorly or Undifferentiated | 1.683 | 1.367–2.072 | <0.001 | 3.2 |
| Unknown (X) | 1.024 | 0.799–1.313 | 0.853 | 0.1 |
| Pathologic T category | <0.001 | |||
| T1 | Reference | 0 | ||
| T2 | 1.477 | 1.304–1.673 | <0.001 | 2.3 |
| T3 | 1.802 | 1.615–2.011 | <0.001 | 3.8 |
| T4 | 1.976 | 1.680–2.325 | <0.001 | 4.7 |
| Pathologic N category | <0.001 | |||
| N0 | Reference | 0 | ||
| N1 | 1.989 | 1.802–2.195 | <0.001 | 2.8 |
| N2 | 3.038 | 2.682–3.441 | <0.001 | 5.7 |
| N3 | 4.582 | 3.876–5.416 | <0.001 | 10 |
| No. of nodes retrieved | <0.001 | |||
| 0–9 | Reference | 3.7 | ||
| 10–14 | 0.763 | 0.687–0.847 | <0.001 | 1.7 |
| 15–24 | 0.615 | 0.550–0.687 | <0.001 | 0.4 |
| >25 | 0.557 | 0.477–0.651 | <0.001 | 0 |