Figure 8.

Glucose decreases polyunsaturated PC plasmalogen species. Isolated mouse islets (A) or MIN6 cells (B) were stimulated with either 2 mM (white bars), or 20 mM glucose (grey bars) for 1 h. Total cellular lipids were extracted and then subjected to MS, as per Methods. Results are expressed as percent of total major phospholipids. *p < 0.05; **p < 0.01; ***p < 0.001 Student's unpaired t-test corrected for multiple comparisons (Holm Sidak); n = 8–9 experiments (A) or 6–8 experiments (B).