Figure 2.

LPS-induced STAT3 phosphorylation. A: number of pSTAT3 positive cells in hypothalamic arcuate nucleus (ARC) and B: representative photomicrographs of ARC 2 h after saline or LPS (100 μg/kg, ip) injection in LepR reporter mice (red), showing pSTAT3 expression (green). 3V = third ventricle. Scale bar: 50 μm 2-tailed Student's t test was performed. Data are expressed as mean ± SEM. (n = 6). *p < 0.05: Saline vs LPS.