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PI3K p110α catalytic subunit is not required for LPS-induced hypophagia and weight loss. Cumulative food intake 2, 14 and 24 h (A) and 24 h changes in body weight (B) in p110α loxP and LepRΔp110α mice treated with saline or LPS (100 μg/kg, ip). Two-way ANOVA followed by Tukey's post hoc test was performed. Data are expressed as mean ± SEM. (n = 8/group). *p < 0.05: p110α loxP Saline vs p110α loxP LPS; #p < 0.05: LepRΔp110α Saline vs LepRΔp110α LPS.
