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. 2016 Mar 19;5(6):379–391. doi: 10.1016/j.molmet.2016.03.003

Figure 8.

Figure 8

PI3K p110β catalytic subunit is required for LPS-induced hypophagia and weight loss. Cumulative food intake 2, 14 and 24 h (A) and 24 h changes in body weight (B) in p110α + β loxP and LepRΔp110α+β mice, after saline or LPS (100 μg/kg, ip) injection. Two-way ANOVA followed by Tukey's post hoc test was performed. Data are expressed as mean ± SEM. (n = 8/group). *p < 0.05: p110α + βloxP Saline vs p110α + βloxP LPS; a p < 0.05: p110α + βloxP LPS vs LepRΔp110α+β LPS; #p < 0.05: LepRΔp110α+β Saline vs LepRΔp110α+β LPS.