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. 2016 Apr 11;5(6):422–432. doi: 10.1016/j.molmet.2016.04.001

Figure 3.

Figure 3

The progressive lipodystrophy of adipocyte Raptor KO mice associates with hepatic steatosis and insulin intolerance. (A) Lean tissue mass of KO and wt mice at ∼12 weeks of age. (B) Representative images of liver from KO and wt mice at ∼12 weeks. (C) Representative H&E images of liver from KO and wt mice. (D) Western blots of liver lysate for indicated proteins. (E) ITT and GTT of adult KO and wt mice. (F) Serum chemistry levels of FFA, TG, and Cholesterol for adult wt and KO mice on chow diet. (G) Serum insulin levels for adult wt and KO mice. (H) Serum adiponectin levels for adult wt and KO mice. (Data were analyzed by Student's t-test. Values expressed as mean + SEM. *p < 0.05; **p < 0.01; ***p < 0.001).