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New approaches to enhance MSC-mediated tissue repair. a | Guided homing of MSCs to bone surface using an integrin-binding peptidomimetic ligand conjugated with the ‘bone-seeking’ bisphosphonate, alendronate (LLP2A-Ale). b | MSC-derived ECM co-administered with MSCs to enhance MSC retention and healing of bone defects Abbreviations: ECM, extracellular matrix; MSC, mesenchymal stem cells.
