Table 5.

Liver-weight/Body-weight change in the rats following daily oral doses of 3TC for 45 days^#

Lamivudine dose (mg/kg/day)	Liver/Body weight ratio (x 10-5)
0.0	3.4683 ± 0.051
4.0	3.4950 ± 0.077
20.0	3.5900 ± 0.065
100.0	3.6200 ± 0.055
500.0	4.0067 ± 0.102*‡

^#Values are means ± S.E.M. Mean significantly different, from the control

^*p<0.01, from 4mg/kg

^∆p<0.05, p<0.01 otherwise p>0.05 (not significant) when compared with the control.