Table 4.

Hematologic and Infectious Toxicity

Toxicity	Grade 3-4				Grade 4 Only
	Patients		No. of Episodes	% of Cycles	Patients		% of Cycles
	No.	%			No.	%
Hematologic
Neutropenia	43	73		17	30	51	9.0
Thrombocytopenia	20	34		7.4	9	15	2.1
Anemia	9	15		3.0	1	1.7	0.2
Infection*
Pneumonia/bronchitis	6	10	6
Urinary tract	1	2	1
Other infection†	2	3	2
Any infectious event‡	9	15	9
Fever
Neutropenic fever	6	10	6
Febrile, non-neutropenic	2	3	3
Any febrile or infectious event§	14	24	18

^*All infectious toxicity was grade ≤ 3.

^†Other infection: orodental (n = 1), wound (n = 1).

^‡Total of pneumonia/bronchitis, urinary tract, and other infections.

^§Total of neutropenic and non-neutropenic febrile events and infectious events.