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. 2016 May 23;15:87. doi: 10.1186/s12934-016-0488-5

Table 1.

List of strains with the highest specific antibody product yields

Strain number Added elements Strain Specific product yield (µg ml−1OD600−1) Relative frequencya P valueb Fold-change relative to wild-typec
154 CPR5-P GPD Δopi1 0.2027 0.2 0.000002 10.22
157 CPR5-P KAR2 Δopi1 0.1992 0.15 0.000159 10.15
155 CPR5-P GAL1 Δopi1 0.1579 0.1 0.000560 7.99
153 CPR5-P TEF Δopi1 0.1525 0.075 0.000036 7.66
156 CPR5-P PDI1 Δopi1 0.1424 0.05 0.007624 7.15
170 ERO1-P GAL1 Δopi1 0.1226 0.05 0.020502 6.13
212 SIL1-P GAL1 Δopi1 0.1223 0.05 0.021128 5.53
162 PDI1-P TEF Δopi1 0.1208 0.075 0.279237 6.09
206 LHS1-P GPD Δopi1 0.1163 0.05 0.299870 5.88
402 LHS1-P KAR2 + SIL1-P KAR2 Δopi1 0.1139 0 0.011316 5.73
83 None Δopi1 0.0886 0.075 4.47
73 None wt 0.0199 0 1

The data represent the mean value of the experiments conducted with 0.5 and 2 % galactose induction at 30 °C

aRelative frequency in the 95th percentile of Δopi1-strains

bCalculated with the nonparametric equivalent of t test, Wilcoxon signed rank test using the Δopi1-strain without added elements as the reference

cAverages of the fold-changes relative to wild-type