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. 2016 May 23;8:59. doi: 10.1186/s13073-016-0316-x

Fig. 1.

Fig. 1

Milestones on the path towards somatic genetic therapies for Duchenne muscular dystrophy that rely on viral-based DMD editing. The time marks correspond to the first release date of the referenced articles (for example, advanced online publication). AdV adenoviral vector, CRISPR–Cas9 clustered regularly interspaced short palindromic repeat-associated Cas9 nuclease, DMD Duchenne muscular dystrophy, DSB double-stranded DNA break, HE homing endonuclease, rAAV recombinant adeno-associated virus, TALE transcription activator-like effector