Table 2.

Circulating levels of total adiponectin and risk of multiple myeloma^a

	Quartileb				Ptrend
	Q1	Q2	Q3	Q4
Total adiponectin
No. of cases	183	178	139	124
No. of controls	311	311	311	313
Base model
Replication setc	1.0 (ref)	0.88 (0.64-1.21)	0.74 (0.53-1.02)	0.68 (0.48-0.96)	0.020
Combined setd	1.0 (ref)	0.95 (0.73-1.24)	0.74 (0.56-0.97)	0.64 (0.47-0.85)	0.001
Multivariate model including body mass index	1.0 (ref)	0.95 (0.72-1.24)	0.73 (0.55-0.97)	0.64 (0.47-0.87)	0.001

^aOdds ratios (ORs) and 95% confidence intervals (CIs) were estimated using conditional logistic regression models.

^bQuartile cut points were defined based on the distribution of cohort- and sex-adjusted analyte levels among controls, as follows: Q1, ≤8.64 μg/mL; Q2, 8.65-12.79 μg/mL; Q3, 12.80-17.79 μg/mL; Q4, ≥17.80 μg/mL.

^cExcluding PLCO

^dIncluding PLCO