Figure 2.
Alterations of distal colon SM contraction. (a-f) Representative traces of spontaneous, 1 μmol/L Cch induced and 20 mmol/L KCl induced contractions of SM strips. (g-i) Summary data showing the average tension, amplitude, and frequency of spontaneous and KCl enhanced contractions. (j-l) Summary data showing the average tension, amplitude, and frequency of Cch enhanced contractions. Data are mean ± SE of n (controls, n = 8 and DSS, n = 7) independent SM strips. *P < 0.05. SM: Smooth muscle; SE: Standard error; Cch: Carbachol; DSS: Dextran sulfate sodium.